Neonatal periventricular leukomalacia: current perspectives
نویسندگان
چکیده
منابع مشابه
Periventricular leukomalacia in a neonatal calf
A 10-day-old, Japanese Black, female calf had shown astasia since just after birth. Focal symmetrical periventricular malacic lesions of the cerebrum and suppurative arthritis of the left hip joint were observed in macroscopic examination. Histologically, the cerebral lesions were confirmed as periventricular leukomalacia (PVL). The location and histological features of the lesions were similar...
متن کاملNeonatal periventricular leukomalacia: real-time sonographic diagnosis with CT correlation.
The utility of real-time sonography in the diagnosis of neonatal periventricular leukomalacia (PVL) has been described only recently. Six cases are reported of PVL diagnosed by serial real-time scanning. The sonographic findings were correlated with the computed tomographic findings and the clinical history. In five of six infants in whom scanning was performed, characteristic multiseptated per...
متن کاملAnimal Models of Periventricular Leukomalacia
Periventricular leukomalacia, specifically characterized as white matter injury, in neonates is strongly associated with the damage of pre-myelinating oligodendrocytes. Clinical data suggest that hypoxia-ischemia during delivery and intrauterine or neonatal infection-inflammation are important factors in the etiology of periventricular leukomalacia including cerebral palsy, a serious case exhib...
متن کاملMouse Models of Periventricular Leukomalacia
We describe a protocol for establishing mouse models of periventricular leukomalacia (PVL). PVL is the predominant form of brain injury in premature infants and the most common antecedent of cerebral palsy. PVL is characterized by periventricular white matter damage with prominent oligodendroglial injury. Hypoxia/ischemia with or without systemic infection/inflammation are the primary causes of...
متن کاملPontine hypoplasia in children with periventricular leukomalacia.
BACKGROUND AND PURPOSE The brain stem in patients with periventricular leukomalacia (PVL) appears smaller than normal on MR imaging, but few reports have described this feature, and the number of patients has been relatively small. The present study was conducted to examine the hypothesis that the pons in patients with PVL is smaller than normal. MATERIALS AND METHODS Using MR imaging, we exa...
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ژورنال
عنوان ژورنال: Research and Reports in Neonatology
سال: 2018
ISSN: 1179-9935
DOI: 10.2147/rrn.s125575